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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd913155fa46c2701d0fa0d699704d5a008f07e57325d140816a0f2d79dc88e3' 
  AND token = '3ISbmxojExULizG4Rtm1eC2lbALPSQb73kPw8z1ejrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}