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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e122fcb5f4233a08a2cca756e27d01f6f28c51080f30372fdb9457e3b86f9cf0' 
  AND token = 'VQR/8LQzHP1H5nJ9F9vrqI5d9HNetz/eQmUrYKAvR/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}