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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1147bb261c93fbcd08f729130220d9d485c2c834d0e11d3751822b7cac58422' 
  AND token = 'NBdgjhWqWuOWE88Y2SZBK3JdN+CchlCDSDEQ5kcgHOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}