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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1214cc6ecb9454de5fe59f746bb95e658b390d08d738f7e994d2c879b5b489fd' 
  AND token = '7mVFTtHjukupjRgR4Irf+KnuZ+vdKt8VAQaoKxHQTCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}