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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1d72b126c61c0c77463eccdadb58884e0ddb1c777ff6654dfb9e7acaca9af6' 
  AND token = 'NBWAPOMInISzK4RgOA8kFFGTHE3bmBBjiLvASlaw/ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}