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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643d58756a0c7f6ac0450bb53515a8434d880d72700a66f60b4d010194f98c92' 
  AND token = 'DZ3dWDrCew0n5jUM1a7Ntq/xtBTzPgjiIBJAPzwqDXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}