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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a377836a7ed0279b32a38e7e8c85ca5e06781ea6f057ad71ce789fdba0e3ada9' 
  AND token = '7AqzgKry1hRkadtbtdPJeP//mgSlP27g5ybKUqWTRIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}