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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cae7f27276802b2b2b6eff85fa8aa65e0e0e265310c0de5e498775b1187e5fd9' 
  AND token = '8mf52a/fIcf6s8qjVyoL5/soYVgEXlFoQVqBhpaHFis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}