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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a681e2cf9345b1a08379248dc75f4c01529a77851300d2ff92b0698a34209c1' 
  AND token = '9Fl2mSEwAtcOZE2xBXJxhj6L5TyGr6xGkbbMmGB6HMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}