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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15be47de1f96d8bb817b7d7daba8bf4a30d29c2afcba2adb8d3469dc1e065d16' 
  AND token = '7lQF3+ZV/pT381cTnzQF2ajbbg8tc3K8z/oXPO7Gu0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}