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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f167e3e2c3af34c02d61663f59eeb31b1a7d69cb3cbe1b8e77d3be711538772a' 
  AND token = 'M2RKhaIOhoc/N/XrO2EOF17aozz6MEMESQs9UimoUgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}