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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f567add79f0ef4072a84366adea36959d81c4064b8e19402d9b7a267d404e7' 
  AND token = '2qxRwQYZxM/1e/8RUE0oVnjmoXJrhf6FZGIfUqVw1Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}