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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aef540d1b05c3705406499c0f78d921a05939cde563bf2863953c83bddd0456' 
  AND token = 'JoKAtmP/3b3Qohnxs0jrZXz3h2s6rswPQvPifh3oZUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}