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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd601a9b6cec205002471b9a280dc6f7998a6b18100eb620fde10f51da7741772' 
  AND token = '3LyX4ojJHnXCmKJLwhlMDhjYi1tZZs9efswb6IgwYrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}