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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54e5d6af1fb73da45870b03cdb6d3f2485c5228e894a1d533fc0e6dc88cac39' 
  AND token = 'Otegv45kBCIqNSC5WR9WAPgXzCVDPCZWx5Euy6HGsKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}