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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c2126ebb320818c45f360bd44bd99ce4ac14a74ab8df467e4e976e1b7be0f0' 
  AND token = 'VfVRqBzqim388nupfHW7eB8eueyfUe3pJKBh5oVhbfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}