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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e37b28dfcd13d54cfcc961dec87a74e8cf2fc8af349604b570c69e166cbe9a79' 
  AND token = 'pz4J2vPAyApyEcCLPcbB5OAYd6Ghb5WjjlR7VwR6W3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}