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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c866b648675d276f3a135e6b470cc0da4b48108d375d8fb25b43f2e55382b362' 
  AND token = '6Cduf+cjCk+JKMePANpdFcBmJDiswxfiP9oRBjV39Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}