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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79f75c5024850243075a49a6007c3ceec1c11b51498769ac5d239fc50c9c126d' 
  AND token = '8HyYcs2Iz3ky0Mhdc5WwDkBOzR+rjj0lERNxbeCQ29M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}