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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604ab5e11ed468ce06e646b3b3cfadb18e8f94328be1276c73ffbcac9b34b341' 
  AND token = 'DfEeffe/XsTqNeRUBEW70A/cDDfD57p1Qni51aWJUUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}