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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4626cee008d4def1909677cd4ae70c588a363f18c8f16ec296c9f4f7bd64b08f' 
  AND token = 'M6wEj/gP4lBCIbBa/xOmjA+7LRgOnqXVzkvMen0AgDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}