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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5a88f060838688ece1c976e9e1bd94cbacc8782efc0314e3f5ba6139184d39' 
  AND token = 'IPW0OPCqBWwXLfR0PmdOUOFb/4+Cm31wa3YCY34SK+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}