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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81218ff522a82a669f97b22cb07a192397ff98a1c51d989cb0e1873754fede54' 
  AND token = 'RdnGyQbQAnfgSNy6PqpHVX6MN7xgbQVK0JX3/trgIaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}