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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764a1812e9bd11c5cb7e21032faa56e565bf475dba4af8fe99287a0ba98b728c' 
  AND token = 'Xhl+3kQ0GjmwR9N5rt6IOf7EH4y+PIlj6c1D7VURLOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}