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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a160a69317f04f80f7131d1a8006355f55d1517c5f87890f16ffa084d6b38f' 
  AND token = 'PHjl158nnuXcrnSAqt8LpZ+2UAG7FR7C/MgIxFGabEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}