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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da72eee898cd1b577c4c2014b0b09a86aa2f3e4a35c8129d2edfaa93f7634b20' 
  AND token = 'BPR69piEOBhnAWXAQXSXoXV8GVJihSddRdS4YpWwDBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}