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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4a6b29aebd5c17db1b8ff15583c61f030f0f038dacc11ac12036f95f4ca3279' 
  AND token = 'ak7ubsVL6bEzSlabIws5qbgpoMlo+sOMR5p1iOHbgRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}