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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65cf253a73a3bcd7cb02a06c81a399d47c420135fb6548c84c405f7657e1a620' 
  AND token = 'CYZS6bC8k7XfOsBLR5jWBSog6jb2Yz/xEyn76T8kBII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}