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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e4ec4e7a20b321bab71b6f37a66605998ede813280b38c66817a98148753e7' 
  AND token = 'R0/HIALUfqRzd0u1HVSf8eJNzya3DCcfNpHgcMYeTsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}