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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3224367acbcac331eb9edb28538e02174781e89929b5289ada73e373e7b7bbf' 
  AND token = 'PW6WDQ6WrMX81EMgfFXtvNjV+8tM+yxI9wvjON34rsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00180

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}