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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae49af0c96da4a5e62349eb6c9d2b9270ca23ea50d766e976dac663f797e0f18' 
  AND token = 'ReTX/d9+Z73AvRxnKlX+rt6ciEt03KtIjBj/oIYA2hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}