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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6d5ff4dbf71cf59c72bfde58c25dfab0010456112108200d67409f4efd6c4e' 
  AND token = 'meBKR6HnFdO0LQUtJdMG46G+uKIsYwVWvm3wnjR3H4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}