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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e165142b7db31c60f769fc2ec03de7a9e7c5b33a9a1d16cb243b7087e4f3c0d' 
  AND token = '4KE0Rmi1TGvtDAgiFsvYRhUuYH2X6jPA0mhYiHvkCF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}