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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2210afb9b02779244588fd23a2826983f5421fc48aa91f1abc168c192ebb5b90' 
  AND token = 'AXuw8Dmx3gejotTO0T5gF7/JVhmznUXdCApPtjMUWX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}