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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01458755218d275a1593835a767a5df9510b2c6f7cd37fc85196d1127eae100a' 
  AND token = 'U+C2g6ZrcvY/M9kRkOfn7Grdg0GfsfNjPicQELYj8tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}