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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d12377410f5cc4782d43d2b8ec537f43c4639e7bbe5859776779ec92ad25d9' 
  AND token = 'fmzE38YK3oacWeLWLjR33m+44cqbCAw1fW5spi5RjGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}