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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be38278f4887a57e96a125b338857c0e33cb7ae26cd966554e28e6e87e11b4e8' 
  AND token = '9rC0QE/bdVPrtL776WwtuQ1NGij8oINgXW/vFScIvk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}