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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f7ca4de304a2f6b7804d23171b86c2aca15b7c3b15a0b92da3f289719f5610' 
  AND token = '0NNceqwaVheMPbkTQMvjHDa4kIEiMMPdnNRZaZXsTbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}