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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e3d8e05033b6927dbedb72e106ed1e8353ec94b6fa3e278f365ed060011be26' 
  AND token = 'lFG0u9a/7DqDaQzN/3h1MrL1J6Ul9IxEOB1zPUSCkH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}