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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67de463f482dda190a787010072ae06a497ff51e80d1991e3ce3e37041d43349' 
  AND token = 'UT2K2cpivHrC7tF+ZYymuIY7NseD6yNaeDx3Dy7VTAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}