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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2212c3ff0d3f5c66db0223e4d0230e14be637b34e283cf79320a7a771e342dd7' 
  AND token = '8QzI+4CShcnIyFc+d2MfcsX5jqWAcZiKLb0Sn1x6FLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}