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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac45cf2c02953e69eeb8df0a8b12b20ec3564ef4411ee2e2e5d6c55b89634b05' 
  AND token = 'uyQzNKN3QnWAHA4kYdXEHhWm9sK5OQp/20czPkhUac0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}