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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1e0cc19655dd70fb4d07baa57b9e743fddc85e0e99d3231557e03b81ef970c' 
  AND token = 'ZEbqHoPPgH1RTxkjiNt4NZYxs/l9ISb8haPvNchg0q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}