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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9c283b2511303202e0ab3cb70407d52244d1aedb02cc2f4977aa91f87f1e00' 
  AND token = 'vMeXHQv9+9f8OQzpC7utB4PM/JqJNKH1XYlMKCpXlmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}