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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecaec1647da6fc9e9c9aaecab376a20c29a473979694128d5df59c5d2d66443e' 
  AND token = 'v6qt+SqmkI74a6GxA/OX2d8chhi+01HbH+wQRmWbz8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}