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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af78599f3b8f25310ef6a1f79d66c9217e34c4e442c24bae7439deeb50763e89' 
  AND token = 'T1EN0SAK4UeOD1FnN4ARjxD3Ft5Cmk8DYYOiHoeO0F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}