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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a91e80492759f0f4006c0f5e87255fe0a324753349465496c9721995c2f919c' 
  AND token = '9UeA+gNVlJpDtiRFuQOC0lqjaZccbHZ7QNDNph2cqyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}