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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c14f807eeaf9d49d6a429d315954461de1d54f0bc18d7e2adbf8707a2738d59' 
  AND token = 'DR+kurthCRnHgsiIUrsKI38mk7VuMDuC1AjeaSrEPqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}