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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0550d4924e01be1e8202e73cb2ce9da6cfa6852c5b8d78b2f06df157bda2a9a' 
  AND token = 'R0nQFbiXvVg9uWFyXgKCPl88xiwbF+JrWfebpl0tIac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}