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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca21e2cf79ff52e9c3aa6ebecbe264f368df3d13d22afb4d1120fbc664a12ba' 
  AND token = 'S11nf88Fmd2e5b9h1CdEFC/HXSPUvPwO00C54prUumA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}